[HTML][HTML] Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia

PW Ladenson, JD Kristensen… - … England Journal of …, 2010 - Mass Medical Soc
… lipid and thyroid hormone levels. … eprotirome or placebo for 12 weeks. Patients were
reassessed 4 weeks after discontinuing eprotirome treatment, while they were still receiving statin

Thyroid hormone analogues to treat dyslipidemia

I Tancevski, A Ritsch, P Eller - Clinical Lipidology, 2010 - Taylor & Francis
Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. N. Engl. …
The authors also demonstrate that the combination of statins and eprotirome is safe in humans, …

Thyroid hormone analogs for the treatment of dyslipidemia: past, present, and future

AP Delitala, G Delitala, P Sioni… - Current medical research …, 2017 - Taylor & Francis
… (statins) are the most effective drugs for lowering the serum LDLc concentrationsCitation 5 .
Statin treatmentEprotirome (KB2115) is a thyroid hormone mimetic containing two bromides …

[HTML][HTML] Potential role of thyroid receptor β agonists in the treatment of hyperlipidemia

T Jakobsson, LL Vedin, P Parini - Drugs, 2017 - Springer
… the thyroid gland to start synthesizing thyroid hormones. For … investigating eprotirome for
the treatment of hyperlipidemia in … eprotirome and statins. In all three studies, administration of …

The promise of Eprotirome

AG Unnikrishnan, H Kumar… - Thyroid Research …, 2011 - journals.lww.com
Eprotirome is a recent thyroid hormone analog that has shown benefits in dyslipidemia.… of
Eprotirome were studied in a larger study.This study was done in statin treated dyslipidemia. …

Thyroid hormone analogues for the treatment of metabolic disorders: new potential for unmet clinical needs?

TJ Shoemaker, T Kono, CN Mariash, C Evans-Molina - Endocrine Practice, 2012 - Elsevier
Statins are the mainstay of treatment for hyperlipidemiastatin who demonstrated persistent
LDL levels above 116 mg/ dL. Participants were treated with increasing doses of eprotirome

A potential novel therapeutic addition to statin therapy for dyslipidemia

WB Borden - Current atherosclerosis reports, 2011 - Springer
thyroid hormone experience a lowering of their cholesterol levels, although attempts to utilize
this beneficial action in treating hyperlipidemia … with eprotirome in addition to statin therapy. …

Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo-controlled phase 3 study

B Sjouke, G Langslet, R Ceska, SJ Nicholls… - The lancet Diabetes & …, 2014 - thelancet.com
Eprotirome is a liver-selective thyroid hormone receptor agonist that has been … when added
to conventional statin treatment with or without ezetimibe, but that it … -treated dyslipidemia. …

Thyroid hormone analogues: an update

R Zucchi - Thyroid, 2020 - liebertpub.com
… (T2) has been used with success in rat models of dyslipidemia and NAFLD, … treatment in
48 hypercholesterolemic patients (14). In patients treated with statins, the addition of eprotirome

Thyromimetics: a journey from bench to bed-side

I Tancevski, M Rudling, P Eller - Pharmacology & therapeutics, 2011 - Elsevier
analogs of thyroid hormones with tissue-specific thyroid … At the moment, the treatment of
dyslipidemia seems to be the … patients on statin therapy the further addition of eprotirome led to …